the Wallabies will be forced to field another heavily depleted side against Wales on Sunday (2.15am AEDT) after five more players were injured and two stars returned to their club commitments.
following their 13-10 defeat to Ireland in Dublinthe Wallabies confirmed the list of injured players that are heading home.
Watch every match of the Wallabies, All Blacks and Springboks tours on the home of rugby, Stan Sport. All matches streaming ad-free, live and on demand
Late penalty cruel Wallabies
That could jeopardise his Rugby World Cup hopes with the injury generally meaning a 9-12 month recovery time.
Prop Tupou missed much of the 2022 Super Rugby Pacific season with a calf injury.
Loose forward Rob Valetini will have his ankle scanned after getting injured early in the second half.
LIVE UPDATES: FIFA World Cup 2022, day two highlights
READ MORE: ‘One love’ ploy scrapped amid FIFA threats
Center Hunter Paisami is another who will undergo scans.
He left the field after three minutes with a knee injury.
Hooker Dave Porecki and halfback Nic White will miss the Wales Test with concussion.
Sean Maloney and Morgan Turinui return to delve into all the Autumn Nation Series results as well as reviewing the RWC qualifying results and World Rugby Awards
It’s the second concussion for Porecki in just four months.
And outside back Andrew Kellaway will also return to Australia where he will undergo scans for a suspected fracture of his fifth metatarsal.
The latest throng of injuries comes after center Lalakai Foketi and fullback Tom Banks went down with shin and ankle injuries respectively.
Compounding the selection issues, five-eighth Bernard Foley and lock Will Skelton will be unavailable for Sunday’s match as they return to their club sides.
The Wallabies went on their tour without five-eighth Quade Cooper, center Samu Kerevi and prop Angus Bell, who all suffered injuries in the Rugby Championship.
Outside struck down by injury this season includes Izaia Perese, Folau Fainga’a, Lachie Swinton, Ned Hanigan, Noah Lolesio, Cadeyrn Neville, Izack Rodda, Matt Philip, Rob Leota and Allan Alaalatoa.
“The medics are going to be busy,” Wallabies coach Dave Rennie said.
“It’s a collision sport and a number of those were from collisions. We’re still assessing things. Definitely four of those guys are out and Bobby (Valetini) is likely to be out.”
It’s perhaps not all doom and gloom, however.
Given the sheer quantity of players out with injury, it begs the question of how good the Wallabies might be at full strength.
The Wallabies haven’t been woeful on their tour with the first three matches decided by one point.
“We’ll have to go into the depth of the squad again,” Rennie said.
“I can guarantee there will be guys itching for another opportunity after the Italy effort.”
For a daily dose of the best of the breaking news and exclusive content from the Wide World of Sports, subscribe to our newsletter by clicking here